Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range

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Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range

BACKGROUND In systematic reviews and meta-analysis, researchers often pool the results of the sample mean and standard deviation from a set of similar clinical trials. A number of the trials, however, reported the study using the median, the minimum and maximum values, and/or the first and third quartiles. Hence, in order to combine results, one may have to estimate the sample mean and standard...

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In systematic reviews and meta-analysis, researchers often pool the results of the sample mean and standard deviation from a set of similar clinical trials. A number of the trials, however, reported the study using the median, the minimum and maximum values, and/or the first and third quartiles. Hence, in order to combine results, one may have to estimate the sample mean and standard deviation ...

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BACKGROUND Usually the researchers performing meta-analysis of continuous outcomes from clinical trials need their mean value and the variance (or standard deviation) in order to pool data. However, sometimes the published reports of clinical trials only report the median, range and the size of the trial. METHODS In this article we use simple and elementary inequalities and approximations in ...

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ژورنال

عنوان ژورنال: BMC Medical Research Methodology

سال: 2014

ISSN: 1471-2288

DOI: 10.1186/1471-2288-14-135